- Product Name D-ERYTHRO-SPHINGOSINE
- cas 123-78-4
- purity 99%
Pharmaceutical
Quality products?make an important contribution to long-term revenue and profitability. Factory supply D-ERYTHRO-SPHINGOSINE 123-78-4 with sufficient stock and high standard
1.What is the D-ERYTHRO-SPHINGOSINE ?
Sphingosine (d18:1) has been used:for sphingosine inhalations studies in mice to evaluate its therapeutic potential in respiratory epithelial cellsto investigate its effect on Pseudomonas aeruginosa strainsas a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
-
-
116467-63-1
N-tert-butyloxycarbonylsphingosine
-
-
123-78-4
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol
Conditions
| Conditions | Yield |
|---|---|
|
N-tert-butyloxycarbonylsphingosine;
With
trifluoroacetic acid;
In
dichloromethane;
at 50 ℃;
for 2h;
With
sodium hydroxide; water;
In
dichloromethane;
pH=~ 10;
|
100%
|
|
With
hydrogenchloride; water;
In
tetrahydrofuran;
at 20 - 50 ℃;
for 18h;
|
98%
|
|
With
trifluoroacetic acid;
for 0.5h;
|
90%
|
|
With
water; trifluoroacetic acid;
In
dichloromethane;
at 0 ℃;
for 1h;
|
87%
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 0 ℃;
for 0.25h;
|
81%
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 3h;
|
80%
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 0 ℃;
for 7h;
|
79%
|
|
N-tert-butyloxycarbonylsphingosine;
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
pH=8;
|
64%
|
|
With
trifluoroacetic acid;
In
water;
at 20 ℃;
for 12h;
|
58%
|
|
With
trifluoroacetic acid;
at 0 ℃;
|
|
|
With
trifluoroacetic acid;
at 20 ℃;
|
-
-
103348-49-8
2-azido-sphingosine
-
-
123-78-4
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol
Conditions
| Conditions | Yield |
|---|---|
|
With
hydrogen sulfide;
In
pyridine; water;
for 48h;
Ambient temperature;
|
95%
|
|
With
pyridine; hydrogen sulfide;
In
water;
for 48h;
|
95%
|
|
With
sodium tetrahydroborate;
In
isopropyl alcohol;
for 48h;
Heating;
|
92%
|
|
With
sodium tetrahydroborate;
In
isopropyl alcohol;
for 24h;
Heating;
|
87%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
|
86%
|
|
With
triphenylphosphine;
In
tetrahydrofuran; water;
Ambient temperature;
|
|
|
With
lithium aluminium tetrahydride;
|
|
|
With
hydrogen sulfide; triethylamine;
In
pyridine; methanol;
at 22 ℃;
for 16h;
|
|
|
With
hydrogen sulfide;
In
pyridine;
|
|
|
With
1.3-propanedithiol; triethylamine;
In
methanol;
at 25 ℃;
for 24h;
|
|
|
With
ammonium chloride; zinc;
In
methanol;
at 20 ℃;
for 12h;
|
2.What is the CAS number for D-ERYTHRO-SPHINGOSINE ?
The CAS number of D-ERYTHRO-SPHINGOSINE is 123-78-4.
More information of D-ERYTHRO-SPHINGOSINE 123-78-4 are:
|
CAS?Number |
123-78-4 |
|
Density |
0.94 g/cm3 |
|
Melting Point |
81-82 °C |
|
Boiling Point |
445.922 °C at 760 mmHg |
|
Flash Point |
223.486 °C |
|
Vapor Pressure |
7.96E-10mmHg at 25°C |
|
Refractive Index |
1.5000 (estimate) |
|
HS CODE |
29221985 |
|
PSA |
66.48000 |
|
LogP |
4.62450 |
|
Pka |
11.80±0.45(Predicted) |
3.What are another words for D-ERYTHRO-SPHINGOSINE ?
Synonyms?for?D-ERYTHRO-SPHINGOSINE 123-78-4:4-Octadecene-1,3-diol,2-amino-, (E)-D-erythro- (8CI);4-Octadecene-1,3-diol, 2-amino-,[R-[R*,S*-(E)]]-;(-)-D-erythro-Sphingosine;(-)-Sphingosine;(2S,3R)-Sphingosine;(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol;(4E)-Sphingenine;4-Sphingenine;4-trans-Sphingenine;D-(+)-erythro-4-trans-Sphingenine;D-Sphingosine;D-erythro-C18-Sphingosine;D-erythro-Sphingosine;Erythrosphingosine;Sphingosine;erythro-4-Sphingenine;erythro-C18-Sphingosine;trans-4-Sphingenine;
4.What is the molecular formula of D-ERYTHRO-SPHINGOSINE?
The chemical formula of ?D-ERYTHRO-SPHINGOSINE is?C18H37NO2 which containing 18 Carbon atoms,37 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??D-ERYTHRO-SPHINGOSINE?is 299.497.
5.What is D-ERYTHRO-SPHINGOSINE (123-78-4) used for?
Sphingosine (123-78-4) is an inhibitor of protein kinase C (IC50 = 1-3 μM).1 It is abundant in cell membranes and is an important mediator in various biochemical pathways.2-4
InChI:InChI=1/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+
Relevant articles related to D-ERYTHRO-SPHINGOSINE:
|
Article |
Source |
|
Aziridine-2-carboxylic acid mediated asymmetric synthesis of D-erythro-and L-threo-sphingosine from a common precursor |
Davis, Franklin A.,Reddy, G. Venkat , p. 4349 - 4352 (1996) |
|
A stereoselective synthesis of d-erythro-spingosine. |
Newman , p. 4098 - 4099 (1973) |
6.Buy D-ERYTHRO-SPHINGOSINE with the best price .
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