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DECAMETHONIUM BROMIDE

  • Product Name DECAMETHONIUM BROMIDE
  • cas 541-22-0
  • purity 99%
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1.What is the DECAMETHONIUM BROMIDE ?

crystalline solid

Decamethonium is a depolarizing neuromuscular blocking agent. It is a partial agonist of muscle-type nicotinic acetylcholine receptors (nAChRs). Decamethonium activates α1β1-containing adult mouse muscle-type nAChRs expressed in X. laevis oocytes with an EC50 value of 40 μM using voltage clamp electrophysiology. It is also a nondepolarizing antagonist of neuronal-type nAChRs, inhibiting mouse α7-, α3β2-, α3β4-, and α4β2-containing receptors with IC50 values of 7.4, 405, 28, and 59 μM, respectively. Decamethonoium is a competitive antagonist of α4β2-containing nAChRs expressed in SH-EP1 cells (IC50 = 52 μM for the human receptor). It also inhibits electric eel acetylcholinesterase (AChE) and blocks electrically-evoked tibialis muscle twitches in anesthetized cats with ED95 values of 35 and 70 μg/kg for cats under chloralose and ether anesthesia, respectively. Formulations containing decamethonium have been used to induce paralysis during anesthesia.

2.What is the CAS number for DECAMETHONIUM BROMIDE ?

The CAS number of DECAMETHONIUM BROMIDE is 541-22-0.

3.What are another words for DECAMETHONIUM BROMIDE ?

Synonyms?for?DECAMETHONIUM BROMIDE 541-22-0:1,10-Decanediaminium,N,N,N,N',N',N'-hexamethyl-, dibromide (9CI);Ammonium, decamethylenebis[trimethyl-bromide] (6CI);Ammonium, decamethylenebis[trimethyl-, dibromide (8CI);C 10;C10 (onium compound);Decacuran;Decamethonium bromide;Decamethonium dibromide;Decamethylene-1,10-bistrimethylammonium dibromide;Decamethylenebis[trimethylammoniumbromide];Syncurine;

4.What is DECAMETHONIUM BROMIDE (541-22-0) used for?

antipsychotic

InChI:InChI=1/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2

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